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Gloved hands preparing a sealed Retatrutide research vial

Retatrutide

Lyophilized peptide for research use only.

From CA$80.00

10 mg · 5 mg · 20 mg

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Six pathways

Compounds grouped by the biology under study.

  1. 01

    Metabolic research

    Retatrutide and tirzepatide are studied in incretin-receptor pharmacology; 5-Amino-1MQ is studied as an enzyme target in nicotinamide and adipocyte metabolism.

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  2. 02

    Repair pathways

    BPC-157, GHK-Cu, and thymosin β4 studies describe angiogenesis, fibroblast and extracellular-matrix biology, actin dynamics, and cell migration. Published rodent injury and cell-culture studies provide the predominant evidence.

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  3. 03

    Cellular energy

    MOTS-c, NAD+, and 5-Amino-1MQ are studied in mitochondrial signalling, NAD-dependent redox chemistry, AMPK activation, and substrate utilisation under metabolic stress.

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  4. 04

    Cellular ageing

    NAD+ and GHK-Cu studies describe sirtuin and PARP substrate availability and extracellular-matrix remodelling in ageing models.

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  5. 05

    Neural signalling

    Melanotan II and Ipamorelin studies describe melanocortin and ghrelin-receptor signalling in the CNS and hypothalamic appetite and stress pathways.

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  6. 06

    Performance biology

    Ipamorelin, Tesamorelin, and IGF-1 LR3 studies describe GH-secretagogue and GHRH-receptor pharmacology, IGF-1 receptor signalling, and skeletal-muscle models.

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Explore the evidence.

Study summaries, original sources, and their limitations.

Open evidence library

The Jastreboff et al. trial reported a −24.2% least-squares mean body-weight change at week 48 in 338 adults with obesity, or overweight plus a weight-related condition, without diabetes. Jastreboff et al., NEJM 2023 ↗

The Jastreboff et al. SURMOUNT-1 trial reported a −20.9% mean body-weight change at week 72 in 2,539 adults with obesity, or overweight plus a complication, excluding diabetes. Jastreboff et al., NEJM 2022 ↗